Creating a 3D model of brain tumors to improve treatment
A Bioprinted Volumetric Model of Vascularized Glioblastoma
This study is creating a 3D model of glioblastoma, a tough type of brain cancer, to help researchers see how the cancer cells grow and respond to treatments, which could lead to better ways to fight the disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10929523 on NIH RePORTER |
What this research studies
This research focuses on developing a three-dimensional (3D) model of glioblastoma, a type of aggressive brain cancer, using advanced light-based bioprinting technology. By replicating the complex tumor microenvironment found in patients, the researchers aim to better understand how glioblastoma cells behave and interact. This model will allow for more accurate assessments of tumor growth and response to potential treatments, paving the way for improved drug screening and therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with glioblastoma who are seeking innovative treatment options.
Not a fit: Patients with other types of brain tumors or those not diagnosed with glioblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for glioblastoma, improving outcomes for patients with this challenging condition.
How similar studies have performed: Previous research has shown promise in using 3D models for studying glioblastoma, indicating that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Zhang, Y. Shrike — Brigham and Women's Hospital
- Study coordinator: Zhang, Y. Shrike
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.