Creating a 3D map of colorectal cancer to understand its development across different ages.
A Multimodal 3D Atlas of Colorectal Cancer Across Ages of Onset
This study is looking at how colorectal cancer develops in younger versus older patients by creating a detailed map of the disease, which could help us understand its biology better and lead to new treatments.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project ID | NIH-10994992 on NIH RePORTER |
What this research studies
This research aims to build a detailed three-dimensional molecular atlas of colorectal cancer (CRC) that examines how the disease develops differently in younger and older patients. By analyzing the interactions between cancer-causing microbes and the tumor environment, the project seeks to identify unique molecular features associated with early-onset CRC. Advanced technologies will be used to visualize and map the progression of cancer within tumors, providing insights into how precancerous cells transition to malignant states. This comprehensive approach will help in understanding the disease's biology and potentially guide future treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with colorectal cancer, especially those who are younger than the typical age of onset.
Not a fit: Patients with colorectal cancer who are older and do not have early-onset disease may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for colorectal cancer, particularly for younger patients.
How similar studies have performed: While the approach of creating a 3D molecular atlas is innovative, similar studies have shown promise in understanding other cancers, suggesting potential for success in this area as well.
Where this research is happening
Nashville, UNITED STATES
- Vanderbilt University — Nashville, United States (Active)
Researchers
- Principal investigator: Lau, Ken S — Vanderbilt University
- Study coordinator: Lau, Ken S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.