Creating 3D printed tissues and organs using advanced computer modeling.
Multiscale Computational Modeling to Design Patterned Tissue Assembloids for Biomanufacturing
['FUNDING_R21'] · UNIVERSITY OF VIRGINIA · NIH-10999951
This study is exploring new ways to create complex tissues and organs using advanced technology, which could help patients by making it easier to produce healthy tissues for transplants or healing.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF VIRGINIA (nih funded) |
| Locations | 1 site (CHARLOTTESVILLE, UNITED STATES) |
| Trial ID | NIH-10999951 on ClinicalTrials.gov |
What this research studies
This research focuses on developing innovative computational models to design and fabricate complex tissues and organs through biomanufacturing. By utilizing advanced algorithms and machine learning, the project aims to predict how different types of cells can be combined and organized into specific patterns. Patients may benefit from this research as it could lead to the mass production of functional tissues and organs for transplantation or regenerative medicine. The approach involves engineering cells with synthetic gene circuits to enhance their interactions and adhesion, ultimately improving tissue formation.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions requiring tissue or organ transplants, such as organ failure or severe injuries.
Not a fit: Patients with conditions that do not require tissue engineering or organ replacement may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enable the production of custom tissues and organs for patients in need of transplants.
How similar studies have performed: While the approach is innovative, similar research in tissue engineering has shown promising results, indicating potential for success.
Where this research is happening
CHARLOTTESVILLE, UNITED STATES
- UNIVERSITY OF VIRGINIA — CHARLOTTESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LAZZARA, MATTHEW J — UNIVERSITY OF VIRGINIA
- Study coordinator: LAZZARA, MATTHEW J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.