NIH-funded research R01 grant

Creating 3D printed nipple-areolar complex implants for breast reconstruction

Official title: 3D Bioprinted Nipple-Areolar Complex Implants

Funded at Univ of Maryland, College Park · NIH-11085143 · Data updated 2026-11-12

This study is working on a special implant that can help make breast reconstruction after a mastectomy look more natural by creating a personalized nipple and areola that blends in with your body, using advanced 3D printing technology.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of Maryland, College Park
NIH-funded
Lab location1 site (College Park, United States)
Project startJune 1, 2023
Project endApril 30, 2028
Funding year2025
Award (this year)$561,959
NIH project number5R01HD112031-03
Project IDNIH-11085143 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women who have undergone mastectomy due to breast cancer and are seeking reconstruction options for the nipple-areolar complex.

Less likely to help

Patients who have not undergone mastectomy or those who do not wish to pursue breast reconstruction may not benefit from this research.

What this research studies

This research focuses on developing a personalized, bioresorbable implant for the nipple-areolar complex (NAC) to aid in breast reconstruction after mastectomy due to breast cancer. The project aims to create a hybrid biomaterial implant that mimics the natural shape and texture of the nipple and areola, which often gets overlooked in traditional reconstruction methods. By utilizing advanced 3D bioprinting techniques, the researchers will design and fabricate implants tailored to individual patient anatomy, promoting tissue ingrowth and eventual degradation of the implant to leave behind natural-looking tissue. The study will explore various design parameters to optimize the implants for clinical use.

Why it matters

Potential benefit: If successful, this research could provide women undergoing mastectomy with a more natural and aesthetically pleasing reconstruction option for the nipple-areolar complex.

How similar studies have gone: While the concept of 3D bioprinting for tissue reconstruction is emerging, this specific approach to NAC reconstruction is novel and has not been extensively tested in clinical settings.

Where this research is happening

  • Univ of Maryland, College Park
    College Park, United States
    Active

Researchers

  • Principal investigator: Fisher, John P — Univ of Maryland, College Park
  • Study coordinator: Fisher, John P

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.