Creating 3D models to understand brain injuries and their effects on the body
3D Models of the Blood-Brain Barrier for Studying Trauma-Induced Cerebral and Systemic Injuries
This study is looking at how traumatic brain injuries affect the brain and body by creating special 3D models to see how brain cells and blood vessels interact, which could help find better ways to prevent or treat problems that come after a TBI.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10914098 on NIH RePORTER |
What this research studies
This research focuses on traumatic brain injury (TBI), which can cause significant damage to the brain and other organs. By developing advanced 3D models of the blood-brain barrier, the team aims to better understand how injuries affect the brain and lead to systemic issues. The approach involves studying the interactions between brain cells and blood vessels to uncover the mechanisms of injury and inflammation. This could provide insights into how to prevent or treat the secondary injuries that often follow a TBI.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced a traumatic brain injury, particularly young adults and older patients.
Not a fit: Patients with non-traumatic brain injuries or those who do not have any history of brain injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from traumatic brain injuries and related systemic complications.
How similar studies have performed: Previous research has shown promise in using 3D models to study brain injuries, indicating that this approach could yield valuable insights.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Zheng, Ying — University of Washington
- Study coordinator: Zheng, Ying
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.