Creating 3D models to study human brain development
Leveraging 3D bioprinted organoid constructs to pattern and model human brain development
['FUNDING_R01'] · EMORY UNIVERSITY · NIH-11013293
This study is working on creating special 3D models of the brain using human cells to help us learn more about how the brain develops and how it can be affected by disorders, with the hope that this will lead to better treatments for people with neurological conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EMORY UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11013293 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced 3D bioprinted organoid constructs to better understand human brain development and related neurological disorders. By utilizing human induced pluripotent stem cells, the project aims to overcome current limitations in organoid culture methods that hinder the accurate modeling of brain physiology. The approach involves creating a controlled extracellular environment that mimics the natural conditions of the brain, allowing for more precise studies of neurodevelopment and the effects of various factors on brain health. Patients may benefit from insights gained through this innovative modeling technique, which could lead to improved treatments for neurological conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with neurological disorders or those interested in brain health.
Not a fit: Patients with conditions unrelated to neurological development or those not residing in the research area may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating neurological disorders.
How similar studies have performed: Previous research has shown promise in using 3D organoid models for studying brain development, indicating potential for success in this novel approach.
Where this research is happening
ATLANTA, UNITED STATES
- EMORY UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SLOAN, STEVEN A — EMORY UNIVERSITY
- Study coordinator: SLOAN, STEVEN A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.