NIH-funded research R15 grant

Creating 3D human brain-like structures using stem cells for testing new treatments

Official title: Utilizing Bioprinted Human Stem Cells for Molecular Screening via Multi-Material Strategies

Funded at University of New Hampshire · NIH-11043883 · Data updated 2026-11-12

This study is working on creating tiny brain-like structures from stem cells to help test new treatments for diseases like Alzheimer's and Parkinson's, making it easier to find effective therapies for patients.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionUniversity of New Hampshire
NIH-funded
Lab location1 site (Durham, United States)
Project startSeptember 18, 2024
Project endSeptember 16, 2027
Funding year2024
Award (this year)$460,500
NIH project number1R15EB036822-01
Project IDNIH-11043883 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with neurodegenerative diseases such as Alzheimer's or Parkinson's.

Less likely to help

Patients with non-neurodegenerative conditions or those not diagnosed with Alzheimer's or Parkinson's may not benefit from this research.

What this research studies

This research focuses on developing innovative methods to create 3D structures that mimic human brain tissue using stem cells. By utilizing advanced bioprinting techniques, the project aims to produce organoids that can be used for screening potential therapies for neurodegenerative diseases like Alzheimer's and Parkinson's. The researchers will optimize a special bioink made from various materials to ensure that the stem cells differentiate into functional neurons effectively. This approach could lead to more accurate testing of new drugs and treatments in a lab setting, potentially speeding up the development of effective therapies for patients.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for neurodegenerative diseases, improving the quality of life for patients.

How similar studies have gone: Other research has shown promise in using 3D bioprinting and stem cell technology for drug testing, indicating that this approach could be effective.

Where this research is happening

  • University of New Hampshire
    Durham, United States
    Active

Researchers

  • Principal investigator: Suh, Won Hyuk — University of New Hampshire
  • Study coordinator: Suh, Won Hyuk

Related research

Other NIH-funded projects on the same topics.

  • Calcium signaling proteins and heart disease: mapping how ions shape structure and function

    A research program will study how calcium-binding proteins in the heart change shape and behavior when ions bind, to understand a form of heart disease.

    NIH research University of New Hampshire · Durham, United States · NIH-11626552

  • New iris-to-lens reprogramming to study eye tissue regeneration

    A project at the University of New Hampshire is exploring how eye tissues can regenerate by reprogramming iris cells to lens-like tissue to understand and potentially treat degenerative eye diseases.

    NIH research University of New Hampshire · Durham, United States · NIH-11626549

  • Expansion of New Hampshire’s Workplace Health Surveillance Program

    A state health program is expanding to track and respond to workplace injuries, illnesses, hazards, and deaths, with a focus on lead exposure, opioid overdoses, suicide, infectious diseases, and worker well-being.

    NIH research University of New Hampshire · Durham, United States · NIH-11584750

  • C1ORF150 control of human mast cell activation in urticaria

    A study in people with chronic hives to understand how a specific gene variant (C1ORF150) affects mast cell activation and how this could lead to better treatments.

    NIH research University of New Hampshire · Durham, United States · NIH-11454839

  • Data Science Core to boost multi-omics biomedical research

    A Data Science Core project at UNH aims to strengthen how researchers design experiments, analyze data, and share large multi-omics datasets to accelerate biomedical and bioengineering breakthroughs.

    NIH research University of New Hampshire · Durham, United States · NIH-11415037

  • Molecular and Cellular Phenotyping Core for Biomedical Research

    This grant funds a core facility at UNH that accelerates biomedical and bioengineering research by providing advanced imaging, proteomics, and material-mechanics tools to researchers and students.

    NIH research University of New Hampshire · Durham, United States · NIH-11415033

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.