Creating 3D human brain-like structures using stem cells for testing new treatments
Utilizing Bioprinted Human Stem Cells for Molecular Screening via Multi-Material Strategies
This study is working on creating tiny brain-like structures from stem cells to help test new treatments for diseases like Alzheimer's and Parkinson's, making it easier to find effective therapies for patients.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Hampshire NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11043883 on NIH RePORTER |
What this research studies
This research focuses on developing innovative methods to create 3D structures that mimic human brain tissue using stem cells. By utilizing advanced bioprinting techniques, the project aims to produce organoids that can be used for screening potential therapies for neurodegenerative diseases like Alzheimer's and Parkinson's. The researchers will optimize a special bioink made from various materials to ensure that the stem cells differentiate into functional neurons effectively. This approach could lead to more accurate testing of new drugs and treatments in a lab setting, potentially speeding up the development of effective therapies for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with neurodegenerative diseases such as Alzheimer's or Parkinson's.
Not a fit: Patients with non-neurodegenerative conditions or those not diagnosed with Alzheimer's or Parkinson's may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for neurodegenerative diseases, improving the quality of life for patients.
How similar studies have performed: Other research has shown promise in using 3D bioprinting and stem cell technology for drug testing, indicating that this approach could be effective.
Where this research is happening
Durham, United States
- University of New Hampshire — Durham, United States (Active)
Researchers
- Principal investigator: Suh, Won Hyuk — University of New Hampshire
- Study coordinator: Suh, Won Hyuk
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.