CReATE Motion Center: Cartilage Regeneration for Joint Health in Veterans
Official title: CReATE Motion Center: Cartilage Regeneration using Advanced Technologies to Enable Motion
Funded at Philadelphia VA Medical Center · NIH-11308727 · Data updated 2026-11-12
A VA center in Philadelphia is building new cartilage-regeneration methods to help Veterans move better and reduce arthritis pain.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Philadelphia VA Medical Center NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2026 |
| NIH project number | 5I50RX004845-03 |
| Project ID | NIH-11308727 on NIH RePORTER |
Who could benefit from this research
✓Could help
Veterans and others with arthritis or joint injuries who may benefit from advanced cartilage therapies.
✕Less likely to help
Patients with conditions not related to cartilage loss or those unsuitable for regenerative therapies may not experience direct benefit.
What this research studies
This project creates the CReATE Motion Center at the Philadelphia VA Medical Center to advance cartilage repair and joint regeneration. It brings together experts in orthopaedic surgery, neurosurgery, medicine, bioengineering, and rehabilitation to develop a translational pipeline from basic science to patient care. The center will focus on cell-based therapies, biomanufacturing, and translational science to accelerate clinical use of new cartilage treatments. The effort aims to improve joint function and long-term joint health for Veterans with arthritis or joint injuries. The program will emphasize infrastructure, collaboration, and education to support future patient-focused trials and therapies.
Why it matters
Potential benefit: If successful, the center could lead to new, soon-to-be-available treatments that restore joint function and reduce pain for patients with arthritis or joint injuries.
How similar studies have gone: Previous work in cartilage regeneration and translational musculoskeletal research supports the feasibility of moving regenerative strategies toward clinical use.
Where this research is happening
-
Philadelphia VA Medical Center
Philadelphia, United States Active
Researchers
- Principal investigator: Mauck, Robert L — Philadelphia VA Medical Center
- Study coordinator: Mauck, Robert L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.