Cranial osteopathic manipulation improves brain fluid flow and reduces inflammation
Cranial Osteopathic Manipulative Medicine Enhances Brain Fluid Flow Alleviating Neuroinflammation
This study is looking at how a gentle hands-on treatment called cranial osteopathic manipulative medicine might help improve brain fluid flow and reduce inflammation, which could make life better for people dealing with brain injuries or related issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia College of Osteopathic Medicine NIH-funded |
| Lab location | 1 site (Blacksburg, United States) |
| Project ID | NIH-10945280 on NIH RePORTER |
What this research studies
This research investigates how cranial osteopathic manipulative medicine (cOMM) can enhance fluid flow in the brain and alleviate neuroinflammation. By applying gentle manual force to the head and spine, the treatment aims to release soft tissue restrictions, which may help clear inflammatory molecules associated with conditions like traumatic brain injury. The study will explore the effects of cOMM on the cholinergic system, which is crucial for cognitive function and neurological health. Patients may experience improved quality of life and reduced symptoms related to brain injuries and inflammation.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals recovering from traumatic brain injuries or those experiencing neuroinflammation-related symptoms.
Not a fit: Patients with non-neurological conditions or those not experiencing any brain-related issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic approaches for managing neuroinflammation and improving recovery from brain injuries.
How similar studies have performed: While osteopathic manipulative medicine has been used for various conditions, the specific application of cranial manipulation for neuroinflammation is relatively novel and has not been extensively tested.
Where this research is happening
Blacksburg, United States
- Virginia College of Osteopathic Medicine — Blacksburg, United States (Active)
Researchers
- Principal investigator: Brolinson, Per Gunnar — Virginia College of Osteopathic Medicine
- Study coordinator: Brolinson, Per Gunnar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.