COVID-19 vaccine protection for pregnant people and their babies

COVID-19 Vaccine Effectiveness in Pregnant Women and their Infants

NIH-funded research Kaiser Foundation Research Institute · NIH-11358279

This work looks at whether COVID-19 vaccines given during pregnancy keep pregnant people and their infants from getting COVID-19 or needing hospital care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionKaiser Foundation Research Institute NIH-funded
Lab location1 site (Oakland, UNITED STATES)
Project IDNIH-11358279 on NIH RePORTER

What this research studies

If you are pregnant, researchers will use health records and lab-confirmed COVID-19 results to compare vaccinated and unvaccinated pregnant people for infections and hospitalizations. They will also track infants during their first year to see if maternal vaccination reduces infant COVID-19 and hospital stays, and whether timing by trimester matters. The team will measure vaccination rates over time and identify social, demographic, and geographic patterns among people who do and do not get vaccinated. Data come from the health system's patient records and linked infant health records.

Who could benefit from this research

Good fit: Ideal candidates are pregnant people receiving care in the participating health system and their infants followed during the first year of life.

Not a fit: People who are not pregnant, whose records are not in the participating health system, or whose infants are not followed in the system would not be included or directly benefit from participation.

Why it matters

Potential benefit: If successful, this could clarify whether maternal COVID-19 vaccination protects both parent and baby and help guide timing and outreach for vaccination in pregnancy.

How similar studies have performed: Real-world observational data and some studies suggest maternal COVID-19 vaccination provides protection to mothers and newborns, but more detailed effectiveness and timing data are still needed.

Where this research is happening

Oakland, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions B pertussis infectionB. pertussis infectionBordetella pertussis infection
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.