COSMIC: A Continuous Monitoring Tool for Brain Injury

ContinuOuS Monitoring Tool for Delayed Cerebral IsChemia (COSMIC)

NIH-funded research Columbia University Health Sciences · NIH-11082377

This project is creating an artificial intelligence tool to help doctors quickly spot a serious brain complication called delayed cerebral ischemia in patients who have had a brain hemorrhage.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11082377 on NIH RePORTER

What this research studies

About 30,000 Americans each year experience a type of brain bleed called aneurysmal subarachnoid hemorrhage (SAH), and a significant number of these patients develop a dangerous complication called delayed cerebral ischemia (DCI). It's often hard for doctors to recognize DCI early because its symptoms can be subtle or mistaken for other issues, and current tests are difficult to perform quickly. This project is developing an AI-powered risk score that uses common vital signs to continuously monitor patients and alert doctors to DCI sooner. By improving how quickly DCI is identified, this tool aims to help prevent strokes and reduce the need for overly aggressive treatments.

Who could benefit from this research

Good fit: This research is relevant for patients who have experienced an aneurysmal subarachnoid hemorrhage and are at risk for delayed cerebral ischemia.

Not a fit: Patients without a history of aneurysmal subarachnoid hemorrhage or those not at risk for delayed cerebral ischemia would not directly benefit from this specific tool.

Why it matters

Potential benefit: If successful, this tool could help doctors detect a dangerous brain complication earlier, potentially preventing strokes and improving outcomes for patients recovering from a brain hemorrhage.

How similar studies have performed: Existing DCI prediction models have not offered the necessary timeliness or precision, making this AI-based approach a novel advancement.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.