Coordination hub for brain injury and post-injury epilepsy efforts
Administrative Core
This effort organizes lab work using animal models to follow how the brain changes after an injury and why epilepsy can develop in people who have had a brain injury.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11325392 on NIH RePORTER |
What this research studies
From your perspective, this is the central coordination team that makes sure the three linked projects and the animal and microscopy labs work together smoothly. The team uses the same group of animals to collect imaging and physiological data over time after a brain injury so results match across projects. They stagger animal enrollment to reduce space and resource needs, hold monthly meetings to review progress, and run quarterly meetings to share findings with outside collaborators. By organizing data collection and analysis across projects, the core helps researchers measure how brain networks change over time and how seizures may emerge after injury.
Who could benefit from this research
Good fit: Ideal candidates for related future studies would be people who have recently experienced an acquired brain injury and are at risk of developing epilepsy.
Not a fit: People without a recent brain injury or whose seizures are unrelated to head trauma are unlikely to receive direct benefit from this project.
Why it matters
Potential benefit: If successful, this coordination could speed up discoveries about how brain injuries lead to epilepsy and help guide new ways to prevent or treat post‑injury seizures.
How similar studies have performed: Previous animal work has linked brain network changes to post‑injury seizures, but using a tightly coordinated set of projects sharing the same animals is a novel organizational approach.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Staley, Kevin J. — Massachusetts General Hospital
- Study coordinator: Staley, Kevin J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.