Coordinating team bringing new PET brain imaging tracers to patients
Administrative Core
This project brings new PET brain imaging tracers into first-in-human testing so patients with neurodegenerative proteinopathies can be imaged.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11181307 on NIH RePORTER |
What this research studies
From a patient's perspective, this Administrative Core organizes the people and processes needed to move new PET tracers from the lab into human scans. The team schedules regular meetings, manages shipments of research materials between labs, and handles financial and regulatory tasks. They work to obtain approvals for first-in-human PET tracer use and coordinate with clinical sites on patient recruitment and progress. The core also participates in consortium meetings to keep multiple labs and clinics working together smoothly.
Who could benefit from this research
Good fit: People with suspected or diagnosed neurodegenerative proteinopathies (for example Alzheimer's disease or Parkinson's disease) who can travel to a participating imaging center and tolerate PET scanning are the likely candidates.
Not a fit: People without neurodegenerative proteinopathies, those unwilling to undergo PET imaging or tracer injection, or those unable to access a participating site are unlikely to benefit directly from this core's activities.
Why it matters
Potential benefit: If successful, this work could produce new PET scans that visualize disease-related proteins in the living brain, improving diagnosis and ability to track neurodegenerative diseases.
How similar studies have performed: Previous programs translating PET tracers for amyloid and tau imaging have successfully moved tracers into human use, so the translational pathway is established though each new tracer remains novel.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Mach, Robert H — University of Pennsylvania
- Study coordinator: Mach, Robert H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.