NIH-funded research U01 cooperative agreement

Coordinating Research on Emerging Arboviral Threats in the Neotropics II

Official title: Coordinating Research on Emerging Arboviral Threats Encompassing the Neotropics II (CREATE-NEO II)

Funded at University of Texas Med Br Galveston · NIH-11612769 · Data updated 2026-11-12

A multi-site effort to understand and respond to arboviruses like dengue, Zika, and Oropouche in the neotropics and prevent outbreaks from reaching the US.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Texas Med Br Galveston
NIH-funded
Lab location1 site (Galveston, United States)
Project startJune 1, 2020
Project endJune 30, 2031
Funding year2026
Award (this year)$32,400
NIH project number3U01AI151807-06S3
Project IDNIH-11612769 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include individuals in arid, urban, or rural settings within the neotropics where arboviruses are emerging, as well as communities participating in surveillance and diagnostic efforts.

Less likely to help

Participants not directly involved in surveillance or who are in locations without arbovirus activity may not benefit.

What this research studies

This program brings partners in the US, Brazil, Panama, and new collaborators in several countries to study how environmental changes and animal hosts influence arbovirus spillover and spread. Researchers will collect samples from humans, wildlife, and mosquitoes across diverse sites and use diagnostics and phylogenetic modeling to map risk. The project aims to uncover how extreme weather and landscape patterns affect transmission and to build coordinated responses that can prevent or blunt introductions of arboviruses into the US. It involves establishing cross-border collaborations, data sharing, and methodological approaches to track and respond to arboviral threats in real time.

Why it matters

Potential benefit: If successful, the project could improve early detection and prevention of arboviral outbreaks, protecting public health in the US and the neotropics.

How similar studies have gone: Previous coordinated surveillance efforts have improved understanding of arbovirus dynamics, but this program expands regional collaboration and real-time response capabilities.

Where this research is happening

  • University of Texas Med Br Galveston
    Galveston, United States
    Active

Researchers

  • Principal investigator: Vasilakis, Nikos — University of Texas Med Br Galveston
  • Study coordinator: Vasilakis, Nikos

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.