Coordinating pediatric eye research for conditions like lazy eye and crossed eyes

Pediatric Eye Disease Investigator Group Coordinating Center

NIH-funded research Jaeb Center for Health Research, INC. · NIH-11285219

This project runs a national network that conducts clinical research to find better treatments for children with amblyopia, strabismus, and other childhood eye problems.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJaeb Center for Health Research, INC. NIH-funded
Lab location1 site (Tampa, UNITED STATES)
Project IDNIH-11285219 on NIH RePORTER

What this research studies

From a parent's point of view, this program links more than 100 clinics and over 300 eye doctors so children with eye conditions can join well-organized research studies close to home. The coordinating center helps design trials and observational studies, enroll children, collect data, and make sure follow-up visits and testing are done the same way across sites. Over the years the network has completed many randomized trials and published results that changed care for conditions like lazy eye, crossed eyes, pediatric cataract, and retinopathy of prematurity. Joining a study usually means regular visits to a participating clinic, simple vision tests, and following the treatment or monitoring plan the study uses.

Who could benefit from this research

Good fit: Children from infancy through about 11 years old who have amblyopia (lazy eye), strabismus (crossed or misaligned eyes), pediatric cataract, ROP, or other childhood eye conditions and who receive care at a participating clinic are typical candidates.

Not a fit: Adults, children without eye disorders, or children whose rare conditions are not addressed by current PEDIG protocols would not be eligible and are unlikely to benefit directly from these studies.

Why it matters

Potential benefit: If successful, this work can lead to clearer treatment guidelines and better vision outcomes for children with common pediatric eye conditions.

How similar studies have performed: Yes — PEDIG has completed dozens of randomized trials and published many papers that have already changed clinical practice for pediatric eye care, so this continues a proven approach.

Where this research is happening

Tampa, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.