Coordinating liquid biopsy efforts for early cancer detection
Official title: Precompetitive Collaboration on Liquid Biopsy for Early Cancer Assessment: Data Management and Coordinating Unit
Funded at Fred Hutchinson Cancer Center · NIH-11176106 · Data updated 2026-11-12
This project brings together labs and hospitals to standardize and share blood-based cancer tests so they can find cancer earlier for people at risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 22, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $792,000 |
| NIH project number | 5U24CA288185-03 |
| Project ID | NIH-11176106 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are people enrolled in partner clinics or studies, such as adults at higher risk for cancer or those willing to provide blood samples for test validation.
✕Less likely to help
People who are not enrolled at a participating site or who have cancers that do not shed detectable markers into the blood are less likely to benefit directly.
What this research studies
As a patient, you should know this project organizes and coordinates teams working on blood-based cancer tests called liquid biopsies. They will help design studies, manage and share data, and apply modern statistics and AI tools so results from different labs can be compared. The work covers many types of markers in blood—like tumor DNA, circulating tumor cells, tiny vesicles, proteins, and metabolites—and aims to validate these tests across different populations and cancer types. By standardizing methods and pooling data, the consortium hopes to make liquid biopsy results more reliable and easier to use in clinical care.
Why it matters
Potential benefit: If successful, this could lead to more reliable blood tests that detect cancers earlier and reduce unnecessary follow-up from false positives.
How similar studies have gone: Some prior liquid biopsy efforts have shown promising early detection for certain cancers, but results vary and broader standardized validation is still needed.
Where this research is happening
-
Fred Hutchinson Cancer Center
Seattle, United States Active
Researchers
- Principal investigator: Zheng, Yingye — Fred Hutchinson Cancer Center
- Study coordinator: Zheng, Yingye
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.