Coordinating efforts to understand serious lung infections
Administrative Core
This program brings together teams to learn why some serious pneumonias don't get better with treatment and to share results that could help people with pneumonia.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11248050 on NIH RePORTER |
What this research studies
Researchers are combining high-throughput biological measurements (omics) with computer modeling to look at how pathogens and the lung’s alveolar cells interact in serious pneumonia. The Administrative Core organizes teams, schedules experiments, and ensures data from the different projects are integrated and usable. It also coordinates communication among investigators and with NIH staff and shares processed data with the wider pneumonia research community. From a patient perspective, the Core helps turn complex lab findings into information that can move toward better care.
Who could benefit from this research
Good fit: People hospitalized with serious pneumonia, especially those whose infection is not improving with standard treatments, would be the most relevant candidates for studies under this center.
Not a fit: Patients with mild, self-limited pneumonia treated entirely as outpatients or those without lung infection are unlikely to benefit directly from this center’s work.
Why it matters
Potential benefit: If successful, this work could reveal why some pneumonia cases fail standard therapy and point toward more targeted treatments for those patients.
How similar studies have performed: Related systems-biology and omics approaches have produced important biological insights into infections, though translating those findings into new treatments is still an active process.
Where this research is happening
Chicago, United States
- Northwestern University — Chicago, United States (Active)
Researchers
- Principal investigator: Wunderink, Richard G — Northwestern University
- Study coordinator: Wunderink, Richard G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.