Coordinating efforts to test new cancer medicines for children
Pediatric Oncology In Vivo Testing Program Coordinating Center
This effort brings together experts to help find new ways to treat childhood cancers by testing adult cancer medicines in pediatric settings.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jackson Laboratory NIH-funded |
| Lab location | 1 site (Bar Harbor, United States) |
| Project ID | NIH-11124780 on NIH RePORTER |
What this research studies
This initiative aims to improve outcomes for children with cancer by coordinating a program that tests targeted anti-cancer medicines, originally developed for adults, to see how well they work for pediatric cancers. Our team at The Jackson Laboratory and Seven Bridges Genomics will manage the data and logistics for this testing program. We will work with pharmaceutical companies, regulatory agencies, and other researchers to make sure these new medicines are thoroughly checked. The ultimate goal is to advance precision medicine, which means finding the right treatment for each child's specific cancer.
Who could benefit from this research
Good fit: This grant focuses on research that could benefit children and young adults with cancer, particularly those whose cancers might respond to targeted therapies.
Not a fit: Patients whose cancers are not targeted by the specific adult anti-cancer agents being tested in this program may not directly benefit from this particular research.
Why it matters
Potential benefit: If successful, this work could lead to new and more effective treatment options for children battling various forms of cancer.
How similar studies have performed: While this specific coordinating center is new, the concept of testing adult cancer drugs for pediatric use is an ongoing area of research with some prior successes in identifying new treatment avenues.
Where this research is happening
Bar Harbor, United States
- Jackson Laboratory — Bar Harbor, United States (Active)
Researchers
- Principal investigator: Bult, Carol J — Jackson Laboratory
- Study coordinator: Bult, Carol J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.