Coordinating efforts to improve lung disease treatments using stem cells
Official title: Adminstrative Core
Funded at Boston University Medical Campus · NIH-11046598 · Data updated 2026-11-12
This study is all about bringing together scientists to work on new ways to understand and treat lung diseases using special stem cells, which could lead to better treatments for patients like you.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | March 1, 2024 |
| Project end | February 28, 2029 |
| Funding year | 2025 |
| Award (this year) | $427,603 |
| NIH project number | 5P01HL170952-02 |
| Project ID | NIH-11046598 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit are individuals affected by lung diseases who may be eligible for new therapeutic approaches developed through this research.
✕Less likely to help
Patients with non-lung-related conditions or those not affected by lung diseases may not receive any benefit from this research.
What this research studies
This research focuses on managing and supporting various projects aimed at understanding and treating lung diseases through the use of pluripotent stem cells. The Administrative Core will facilitate collaboration among researchers, ensuring effective communication and coordination of efforts. It will oversee the development of gene-edited stem cell lines and therapeutic approaches, while also managing resources and data sharing. Patients may benefit from advancements in lung disease treatments that arise from these coordinated efforts.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for lung diseases through innovative stem cell therapies.
How similar studies have gone: Other research initiatives utilizing pluripotent stem cells for lung disease treatment have shown promising results, indicating a potential for success in this approach.
Where this research is happening
-
Boston University Medical Campus
Boston, United States Active
Researchers
- Principal investigator: Kotton, Darrell N. — Boston University Medical Campus
- Study coordinator: Kotton, Darrell N.
Related research
Other NIH-funded projects on the same topics.
-
Creating a detailed map of early lung cancer changes
This study is looking at early changes in lung tissue that can lead to cancer, specifically focusing on common types of lung cancer, and it's for patients who want to help researchers understand these changes better so they can improve early detection and treatment.
-
Telomere trouble in ALT cancers: what causes damage and how it happens
Researchers are studying why some cancer cells use ALT to lengthen telomeres and how replication stress damages telomeres, aiming to uncover key processes that could be targeted in patients.
-
IL-6 signaling, lung injury, and post-TB lung disease in TB/HIV
This grant tests how a specific immune signal (IL-6) relates to lung damage after tuberculosis in people with and without HIV, aiming to understand who is at risk for lasting lung problems.
-
IL-6 signaling and lung injury after TB and HIV co-infection
This project looks at how a common immune signal called IL-6 relates to lung injury after TB treatment, especially in people who also have HIV.
-
LEAD Africa: advancing Alzheimer’s research across Africa
A new project aims to build Alzheimer’s disease research capabilities in Africa to improve understanding and care for people with dementia.
-
Leading AD and related dementias research in Africa
A multi-country effort aims to build Africa’s capacity to study Alzheimer’s disease and related dementias using scalable, low-cost methods.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.