Coordinating efforts to find markers for memory and thinking problems caused by blood vessel disease
VCID Biomarkers Coordinating Center
This project helps organize a large group of medical centers working to find reliable signs in the body that tell us about memory and thinking problems caused by small blood vessel disease in the brain.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10698390 on NIH RePORTER |
What this research studies
This project supports a large group of medical centers working together to identify reliable markers for memory and thinking problems linked to small blood vessel disease in the brain. We aim to create a clear plan for testing these markers to ensure they are ready for use in future patient studies. Our team will help coordinate all the activities, manage the data, and encourage diverse patient participation across all sites. The ultimate goal is to speed up the process of finding new treatments for these conditions.
Who could benefit from this research
Good fit: Patients who might benefit from future clinical trials related to vascular cognitive impairment and dementia (VCID) due to small vessel disease are the target population for this research.
Not a fit: Patients not affected by vascular cognitive impairment and dementia due to cerebral small vessel disease may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to earlier and more accurate detection of brain changes, helping doctors find better treatments for memory and thinking problems.
How similar studies have performed: The Coordinating Center has a strong track record in setting rigorous standards for biomarker validation in previous phases of this consortium.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Greenberg, Steven M — Massachusetts General Hospital
- Study coordinator: Greenberg, Steven M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.