Coordinating center for oxytocin treatments for injury-related pain
Administrative Core
This project helps teams develop oxytocin-based treatments to reduce long-term pain after injury for people with persistent pain from accidents or surgery.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project ID | NIH-11314599 on NIH RePORTER |
What this research studies
From a patient's view, this project organizes researchers across three institutions to speed development of oxytocin therapies for pain after injury. It creates shared data systems and quality checks, including REDCap databases for both lab and clinical work, documentation of preclinical experimental plans, and automated manuscript checks. The Core also manages shared equipment, animal husbandry, and surgical facilities and helps allocate resources so studies run smoothly. By keeping labs and clinics aligned, the goal is to make findings more reliable and ready for human testing.
Who could benefit from this research
Good fit: Ideal candidates would be people with persistent pain following an injury or surgery who could enroll in the P01's clinical studies of oxytocin-based treatments.
Not a fit: People without injury-related pain, those ineligible for clinical trials, or those with contraindications to oxytocin may not receive direct benefit from this project.
Why it matters
Potential benefit: If successful, this could lead to more reliable research and faster development of oxytocin-based treatments that reduce chronic pain after injury.
How similar studies have performed: Some early laboratory and small human studies suggest oxytocin can affect pain, but evidence is limited and this coordinated program is relatively novel in linking preclinical and clinical work.
Where this research is happening
Winston-Salem, United States
- Wake Forest University Health Sciences — Winston-Salem, United States (Active)
Researchers
- Principal investigator: Martin, Thomas Jeffrey — Wake Forest University Health Sciences
- Study coordinator: Martin, Thomas Jeffrey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.