Coordinating center for new HIV prevention tools and strategies
Official title: HIV Prevention Trials Network Leadership and Operations Center
Funded at Family Health International · NIH-11466553 · Data updated 2026-11-12
This project runs clinical trials to bring new HIV prevention options to people at risk worldwide, including young people, women, men who have sex with men, transgender women, sex workers, and people who inject drugs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Family Health International NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | June 1, 2006 |
| Project end | November 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $389,554 |
| NIH project number | 3UM1AI068619-20S3 |
| Project ID | NIH-11466553 on NIH RePORTER |
Who could benefit from this research
✓Could help
HIV-negative people at higher risk—including sexually active young adults, women in high‑prevalence regions, men who have sex with men, transgender women, sex workers, and people who inject drugs—are ideal candidates.
✕Less likely to help
People living with HIV or those with very low risk of exposure are unlikely to benefit directly from these prevention trials.
What this research studies
This program organizes and manages clinical trials testing new prevention approaches such as long‑acting antiretroviral injections, products that prevent HIV plus pregnancy or other infections, and antibody-based preventives. The team designs studies, coordinates sites around the world, and partners with local clinics and communities to enroll people at higher risk. Priority populations include women in sub‑Saharan Africa, young men and women, men who have sex with men, transgender women, sex workers, and people who inject drugs. Trial results are used to identify safe, practical prevention options that could be offered in everyday care.
Why it matters
Potential benefit: Could lead to safer, longer‑lasting, and combined prevention options that lower HIV risk for people at high risk of infection.
How similar studies have gone: Oral PrEP and recent long‑acting injectable PrEP have already reduced HIV infections, and this program builds on that progress by testing new long‑acting agents, multipurpose prevention products, and antibody approaches.
Where this research is happening
-
Family Health International
Durham, United States Active
Researchers
- Principal investigator: Landovitz, Raphael J — Family Health International
- Study coordinator: Landovitz, Raphael J
Related research
Other NIH-funded projects on the same topics.
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Making HIV prevention and care easier for Ugandan youth
A Ugandan study is testing ways to help adolescents and young adults (15–24) prevent HIV and stay healthy, using long-acting PrEP and youth-friendly services.
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Innovative HIV Prevention and Care Interventions for Adolescents and Young Adults in Uganda
A Ugandan research team is testing practical, youth-focused strategies to help 15-24 year-olds using HIV prevention or treatment services stay healthy and engaged in care.
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Adolescent girls in Uganda: a long-term look at how money empowerment and family support affect HIV prevention, care, and mental health
A long-term study in rural Uganda will test whether an intervention that combines economic empowerment and family strengthening can help HIV-negative and HIV-affected adolescent girls move safely into young adulthood.
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Long-term HIV prevention and mental health support for adolescent girls and young women in Uganda
A long-term program in rural Uganda tests if combining economic support and family strengthening helps teenage girls stay HIV-free and improve mental health as they grow into young adults.
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Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
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Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.