Coordinating center for new HIV prevention tools and strategies

HIV Prevention Trials Network Leadership and Operations Center

['FUNDING_OTHER'] · FAMILY HEALTH INTERNATIONAL · NIH-11466553

This project runs clinical trials to bring new HIV prevention options to people at risk worldwide, including young people, women, men who have sex with men, transgender women, sex workers, and people who inject drugs.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorFAMILY HEALTH INTERNATIONAL (nih funded)
Locations1 site (DURHAM, UNITED STATES)
Trial IDNIH-11466553 on ClinicalTrials.gov

What this research studies

This program organizes and manages clinical trials testing new prevention approaches such as long‑acting antiretroviral injections, products that prevent HIV plus pregnancy or other infections, and antibody-based preventives. The team designs studies, coordinates sites around the world, and partners with local clinics and communities to enroll people at higher risk. Priority populations include women in sub‑Saharan Africa, young men and women, men who have sex with men, transgender women, sex workers, and people who inject drugs. Trial results are used to identify safe, practical prevention options that could be offered in everyday care.

Who could benefit from this research

Good fit: HIV-negative people at higher risk—including sexually active young adults, women in high‑prevalence regions, men who have sex with men, transgender women, sex workers, and people who inject drugs—are ideal candidates.

Not a fit: People living with HIV or those with very low risk of exposure are unlikely to benefit directly from these prevention trials.

Why it matters

Potential benefit: Could lead to safer, longer‑lasting, and combined prevention options that lower HIV risk for people at high risk of infection.

How similar studies have performed: Oral PrEP and recent long‑acting injectable PrEP have already reduced HIV infections, and this program builds on that progress by testing new long‑acting agents, multipurpose prevention products, and antibody approaches.

Where this research is happening

DURHAM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.