Coordinated data and analysis support for Alzheimer's prevention
Core B: Analytics Core
This project builds rigorous data and statistical tools to better understand what affects people's risk of Alzheimer's disease.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11189704 on NIH RePORTER |
What this research studies
This Analytics Core organizes and harmonizes data across multiple Alzheimer prevention projects so researchers can use the same clear methods. It builds analytic datasets, creates reusable analysis code, and guides teams on choosing complementary statistical approaches. The core applies methods like causal inference, instrumental variables, Mendelian randomization, and quantitative bias analysis to compare different ways of estimating risk. It also helps estimate how changing risk factors or policies could change Alzheimer disease rates across populations.
Who could benefit from this research
Good fit: People concerned about Alzheimer's risk—including older adults or anyone who shares their health and genetic data for research—are the kinds of patients whose data could inform this work.
Not a fit: Patients seeking direct clinical treatment or immediate therapeutic benefit should not expect personal benefit because this core focuses on data analysis rather than delivering care.
Why it matters
Potential benefit: If successful, this work could clarify which risk factors and policies most reduce Alzheimer's cases and help guide prevention strategies.
How similar studies have performed: Techniques like Mendelian randomization and instrumental-variable analyses have been used successfully in other disease areas, though applying them together for Alzheimer's prevention is relatively novel and evolving.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Huang, Chiung-Yu — Boston University Medical Campus
- Study coordinator: Huang, Chiung-Yu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.