NIH-funded research U01 cooperative agreement

Coordinated cancer care for adolescents and young adults with HIV in Zambia

Official title: Integrated delivery of cancer control interventions for adolescents and young adults living with HIV in Zambia

Funded at Implenomics Llcs · NIH-11417071 · Data updated 2026-11-12

This program uses peer supporters, clinician networks, and health-system collaboration to help young people with HIV in Zambia get earlier cancer diagnoses and finish cancer treatment.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionImplenomics Llcs
NIH-funded
Lab location1 site (Marblehead, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2027
Funding year2025
Award (this year)$108,000
NIH project number3U01CA275054-04S1
Project IDNIH-11417071 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents and young adults living with HIV in Zambia, especially those at risk for or diagnosed with Kaposi sarcoma, non-Hodgkin lymphoma, or cervical cancer, are the ideal candidates.

Less likely to help

People who do not have HIV, are older than the target age range, or who cannot access participating clinics in Zambia would not directly benefit from this program.

What this research studies

If I am an adolescent or young adult living with HIV in Zambia, the ARROW program would place peer counselors to support me through screening and treatment, link pediatric and adult HIV and cancer clinicians through peer learning networks, and bring health administrators and policymakers together to solve system barriers. The program will be rolled out in participating clinics and compared to usual care using implementation science methods. Researchers will track whether cancers like Kaposi sarcoma, non-Hodgkin lymphoma, and cervical cancer are detected earlier, whether people complete recommended treatment, and the costs and practical issues of running the program.

Why it matters

Potential benefit: If successful, this could lead to earlier cancer detection and higher treatment completion for adolescents and young adults living with HIV in Zambia.

How similar studies have gone: Peer support and integrated care approaches have helped engagement in HIV and cancer services in other settings, but combining these strategies specifically for adolescents and young adults with HIV in Zambia is relatively new.

Where this research is happening

  • Implenomics Llcs
    Marblehead, United States
    Active

Researchers

  • Principal investigator: Subramanian, Sujha — Implenomics Llcs
  • Study coordinator: Subramanian, Sujha

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.