Controlling nerve activity to treat various health conditions
Nest#4-Nerve Excitation Control Through AC Regulation (NECTAR)
['FUNDING_OTHER'] · CASE WESTERN RESERVE UNIVERSITY · NIH-10918162
This study is exploring a new way to help manage nerve activity using a special type of electrical stimulation, which could lead to better treatments for heart rhythm problems, breathing issues, chronic pain, and urinary troubles.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CASE WESTERN RESERVE UNIVERSITY (nih funded) |
| Locations | 1 site (CLEVELAND, UNITED STATES) |
| Trial ID | NIH-10918162 on ClinicalTrials.gov |
What this research studies
This research investigates a novel method to control nerve activity using electrical stimulation, specifically focusing on a technique called kilohertz frequency alternating current (KHFAC). By rapidly and reversibly downregulating nerve activity, this approach aims to provide new treatment options for conditions such as cardiac arrhythmias, chronic obstructive pulmonary disease (COPD), chronic pain, and urinary issues. The project seeks to develop practical tools for researchers to implement this nerve block technique safely and effectively in clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from cardiac arrhythmias, COPD, chronic neuropathic pain, or urinary sphincter dysfunction.
Not a fit: Patients with conditions not related to nerve activity modulation or those who do not respond to electrical stimulation therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that improve the management of various chronic conditions by providing rapid and reversible nerve control.
How similar studies have performed: Previous research has shown promising results with similar electrical stimulation techniques, indicating potential for success in this novel approach.
Where this research is happening
CLEVELAND, UNITED STATES
- CASE WESTERN RESERVE UNIVERSITY — CLEVELAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VRABEC, TINA LOUISE — CASE WESTERN RESERVE UNIVERSITY
- Study coordinator: VRABEC, TINA LOUISE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Chronic Obstruction Pulmonary Disease, Chronic Obstructive Lung Disease, Chronic Obstructive Pulmonary Disease