Controlling chemical concentrations in the extracellular space using electrochemistry
Spatiotemporal control of concentration gradients with electrochemistry in extracelluar space
This study is exploring new ways to control the levels of important chemicals around bacteria in our bodies, especially in our gut, using tiny sensors, so we can better understand how these changes affect how bacteria behave.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10860976 on NIH RePORTER |
What this research studies
This research focuses on developing advanced methods to control the concentration of important chemical species in the extracellular environment, particularly in relation to microbial biofilms and gastrointestinal microbiota. By utilizing electrochemical nano- and micro-electrodes, the project aims to create precise concentration gradients that can mimic natural conditions, which is crucial for understanding how these gradients influence microbial behavior. The approach combines experimental techniques with numerical simulations to achieve effective control over chemical distributions at microscopic levels.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals with gastrointestinal disorders or conditions influenced by microbial imbalances.
Not a fit: Patients with conditions unrelated to microbial activity or those not affected by extracellular chemical environments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of microbial functions and improve strategies for managing diseases related to microbial imbalances.
How similar studies have performed: Other research has shown promise in using electrochemical methods for controlling chemical environments, suggesting potential success for this novel approach.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Liu, Chong — University of California Los Angeles
- Study coordinator: Liu, Chong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.