Controlling a robotic arm and hand using brain signals for patients with paralysis.

Long-term reliable neuroprosthetic control of a robotic arm and hand using electrocorticography.

NIH-funded research University of California, San Francisco · NIH-10804205

This study is exploring how people with severe limb paralysis can use their brain signals to control a robotic arm and hand, helping them regain some independence in their daily lives without needing to constantly adjust the device.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10804205 on NIH RePORTER

What this research studies

This research investigates how patients with severe limb paralysis, such as those with amyotrophic lateral sclerosis or spinal cord injuries, can use their brain signals to control a robotic arm and hand. By utilizing electrocorticography (ECoG), the study aims to establish a reliable method for these patients to perform daily tasks without needing constant recalibration of the device. The approach focuses on enabling long-term control of the robotic device, allowing patients to regain some independence in their daily activities. The research will compare different methods of decoding brain signals to find the most effective way to achieve stable control.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from severe limb paralysis due to conditions like amyotrophic lateral sclerosis, spinal cord injuries, or brain strokes.

Not a fit: Patients with mild motor impairments or those who do not have severe paralysis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the quality of life for patients with severe paralysis by restoring their ability to perform everyday tasks.

How similar studies have performed: Previous research has shown promise in using brain signals for neuroprosthetic control, indicating that this approach has the potential for success.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Amyotrophic Lateral Sclerosis Motor Neuron Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.