Continued follow-up of TEDDY children and a new case-control group for early childhood diabetes
Limited Competition: Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in The Young Study (TEDDY)
This project keeps tracking children in the TEDDY program and adds a matched case-control group to learn how early-life environment relates to developing childhood diabetes.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Florida NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-11388393 on NIH RePORTER |
What this research studies
This award continues the Data Coordinating Center (DCC) work to maintain contact with TEDDY participants, manage and secure study data, and support clinical sites. The DCC will collect and analyze follow-up information and establish a second nested case-control cohort to compare children who develop diabetes with matched peers. Activities include data management, quality control, statistical analysis, site monitoring, and helping investigators prepare reports and publications. The DCC will also handle communications, maintain study documents and the website, and protect participant confidentiality throughout the process.
Who could benefit from this research
Good fit: Ideal candidates are children already enrolled in the TEDDY program or those at increased genetic risk for type 1 diabetes who are participating in TEDDY follow-up activities.
Not a fit: People not enrolled in TEDDY, adults without childhood-onset diabetes, or those without relevant genetic risk are unlikely to be eligible or receive direct benefit from this work.
Why it matters
Potential benefit: If successful, better long-term data and case-control comparisons could improve understanding of triggers for type 1 diabetes and inform earlier detection or prevention strategies for at-risk children.
How similar studies have performed: Earlier TEDDY cohort work and other longitudinal studies have identified autoantibodies and environmental associations, so this continues and expands a productive, ongoing research effort rather than testing an unproven therapy.
Where this research is happening
Tampa, United States
- University of South Florida — Tampa, United States (Active)
Researchers
- Principal investigator: Krischer, Jeffrey P — University of South Florida
- Study coordinator: Krischer, Jeffrey P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.