Continued follow-up and a new case-control group on environmental causes of childhood type 1 diabetes
Limited Competition: Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in The Young Study (TEDDY)
This project keeps tracking children at risk for early-onset type 1 diabetes and adds a new comparison group to help find environmental factors linked to who develops diabetes and who does not.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Florida NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-11388395 on NIH RePORTER |
What this research studies
If you or your child are part of TEDDY, the Data Coordinating Center will continue collecting health information, lab results, and questionnaire data and will securely store and manage those records. The team will set up a second nested case-control group that compares children who develop type 1 diabetes with matched children who do not, using the collected clinical and laboratory data. Study staff will monitor site data quality, protect patient confidentiality, provide statistical analysis, and help share results and study materials across participating centers.
Who could benefit from this research
Good fit: Ideal candidates are children already enrolled in TEDDY or children with genetic risk for type 1 diabetes whose families can provide clinical data, specimens, and attend follow-up visits.
Not a fit: People without genetic risk for type 1 diabetes or those seeking immediate treatment interventions are unlikely to gain direct clinical benefit from this observational follow-up.
Why it matters
Potential benefit: If successful, this work could clarify environmental triggers of early-onset type 1 diabetes and guide earlier detection or prevention strategies.
How similar studies have performed: Earlier TEDDY work has produced important findings about autoantibodies, infections, and dietary links to type 1 diabetes risk, so this continues a successful, ongoing cohort effort.
Where this research is happening
Tampa, United States
- University of South Florida — Tampa, United States (Active)
Researchers
- Principal investigator: Krischer, Jeffrey P — University of South Florida
- Study coordinator: Krischer, Jeffrey P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.