Continued follow-up and a new case-control group for TEDDY (type 1 diabetes in children)

Limited Competition: Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in The Young Study (TEDDY)

NIH-funded research University of South Florida · NIH-11388394

This project keeps tracking children at risk for type 1 diabetes and adds a new group to compare those who develop diabetes with those who do not.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of South Florida NIH-funded
Lab location1 site (Tampa, United States)
Project IDNIH-11388394 on NIH RePORTER

What this research studies

You or your child would remain in ongoing TEDDY follow-up where health data and biological samples are collected over time. The University of South Florida Data Coordinating Center will gather, secure, and analyze data sent from TEDDY clinical centers and support site quality checks. Staff will visit sites, monitor data accuracy, and provide statistical support for reports and publications. The project will also start a second nested case-control group to compare children who develop type 1 diabetes with matched controls to look for environmental triggers.

Who could benefit from this research

Good fit: Ideal candidates are children already enrolled in TEDDY or children with high genetic risk for type 1 diabetes whose families are willing to provide follow-up information and samples.

Not a fit: People without elevated genetic risk for type 1 diabetes or those with other forms of diabetes such as typical adult-onset type 2 diabetes are unlikely to benefit directly from this project.

Why it matters

Potential benefit: If successful, this work could help find environmental triggers and improve early detection or prevention strategies for type 1 diabetes in children.

How similar studies have performed: Previous TEDDY research has produced important findings about early-life factors linked to type 1 diabetes, and adding a nested case-control cohort uses established methods to expand that knowledge.

Where this research is happening

Tampa, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Brittle Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.