Consortium hub for early liver cancer detection and data coordination
Official title: Consortium on Translational Research in Early Detection of Liver Cancer:Data Management and Coordinating Center (DMCC)
Funded at Fred Hutchinson Cancer Center · NIH-11178110 · Data updated 2026-11-12
This project builds a central hub that helps researchers find and confirm blood and tissue markers to catch liver cancer earlier in people with cirrhosis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 17, 2018 |
| Project end | August 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $700,360 |
| NIH project number | 5U24CA230144-09 |
| Project ID | NIH-11178110 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are people with cirrhosis or other chronic liver disease who are under surveillance for liver cancer or who are willing to donate samples for biomarker research.
✕Less likely to help
People without liver disease or those needing immediate treatment for advanced cancer are unlikely to get direct clinical benefit from this coordinating center.
What this research studies
This coordinating center brings together scientists across hospitals and labs to speed up work on early liver cancer detection. It creates and maintains secure databases and biorepositories where clinical data and patient samples are stored and shared. The center also helps design studies, provides statistical and bioinformatics support (including AI tools), and runs meetings to prioritize the most promising biomarkers. By standardizing procedures and pooling data, the group aims to make validation studies faster and more reliable.
Why it matters
Potential benefit: If successful, this work could help detect liver cancer earlier in high-risk patients and improve how doctors monitor people with cirrhosis.
How similar studies have gone: Previous multi-center biomarker efforts have produced promising leads but translating those markers into routine clinical tests has been challenging and needs coordinated validation.
Where this research is happening
-
Fred Hutchinson Cancer Center
Seattle, United States Active
Researchers
- Principal investigator: Feng, Ziding — Fred Hutchinson Cancer Center
- Study coordinator: Feng, Ziding
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.