Consensus DSC-MRI protocol for brain tumor imaging
Establishing the clinical utility of a consensus DSC-MRI Protocol
['FUNDING_R01'] · UNIVERSITY OF TX MD ANDERSON CAN CTR · NIH-11302696
This project tests a shared MRI method that measures blood volume to help doctors better image and treat people with glioma, a common type of brain tumor.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TX MD ANDERSON CAN CTR (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11302696 on ClinicalTrials.gov |
What this research studies
You would be helping researchers standardize a commonly used MRI scan (DSC‑MRI) that measures relative cerebral blood volume (rCBV) across hospitals. The team will collect scans from multiple centers, define consistent pre‑ and post‑processing steps, and link images to tissue from image‑localized biopsies to confirm what the MRI shows. The work aims to make results more accurate and repeatable so clinicians can more reliably tell tumor growth from treatment effects and predict treatment response. The study will produce clear best‑practice recommendations for clinical use.
Who could benefit from this research
Good fit: Ideal candidates are people diagnosed with glioma who are receiving routine brain MRI and who can have imaging and, when applicable, image‑localized biopsy at a participating center.
Not a fit: Patients without a brain tumor diagnosis or those not getting MRI scans or biopsies at participating hospitals are unlikely to see direct benefit from this project.
Why it matters
Potential benefit: If successful, this could make MRI reports more reliable for people with brain tumors, helping doctors choose better treatment and follow‑up strategies.
How similar studies have performed: Previous studies show DSC‑MRI and rCBV can help grade gliomas and distinguish recurrence from treatment effects, but broad multi‑site standardization is newer and still being established.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TX MD ANDERSON CAN CTR — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: QUARLES, CHRISTOPHER CHAD — UNIVERSITY OF TX MD ANDERSON CAN CTR
- Study coordinator: QUARLES, CHRISTOPHER CHAD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.