Connecting genetic information to personalized cancer treatments
Official title: Matching genotypes with personalized therapies: Development of a decision support infrastructure to augment the value of precision medicine
Funded at Johns Hopkins University · NIH-10893456 · Data updated 2026-11-12
This study is working on a new tool to help doctors use genetic information to find the best treatments for cancer patients more quickly and accurately, so they can provide better care.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $387,351 |
| NIH project number | 5U01CA274631-02 |
| Project ID | NIH-10893456 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are cancer patients whose treatment options could be guided by genetic testing results.
✕Less likely to help
Patients without cancer or those whose conditions do not involve genomic factors may not benefit from this research.
What this research studies
This research aims to improve how clinicians use genetic data to make treatment decisions for cancer patients. By developing a decision support system, the project will automate the matching of genetic findings from next-generation sequencing with targeted therapies, making the process faster and more accurate. The goal is to enhance the integration of genomic and clinical data, ultimately helping doctors provide better care for patients with cancer. The system will be tested in various clinical settings, including community medical centers and ongoing clinical trials.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments for patients based on their genetic profiles.
How similar studies have gone: Previous research has shown promise in using decision support systems for precision medicine, indicating potential success for this approach.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Anagnostou, Valsamo — Johns Hopkins University
- Study coordinator: Anagnostou, Valsamo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.