Concentrated investment to improve health in low-income Philadelphia neighborhoods

Randomized Controlled Trial of Concentrated Investment in Low-Income Neighborhoods to Improve Health

NIH-funded research University of Pennsylvania · NIH-11126053

This project brings coordinated investments in housing, jobs, safety, and services to improve health for adults living in low-income Philadelphia neighborhoods.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11126053 on NIH RePORTER

What this research studies

If you live in a low-income neighborhood in Philadelphia, some neighborhoods will be randomly chosen to receive concentrated investments while others continue as usual. The investments include housing improvements, economic supports, community safety measures, counseling, and expanded local services to address multiple causes of poor health together. Researchers will follow adults in the neighborhoods over time with surveys, health records, and community measures to track changes in wellbeing, stress, and health outcomes. The aim is to reduce the long-standing gaps in health and life expectancy linked to neighborhood conditions.

Who could benefit from this research

Good fit: Adults aged 21 and older who live in the selected low-income neighborhoods in Philadelphia are the intended participants.

Not a fit: People who do not live in the targeted neighborhoods, are under 21, or whose health issues are unrelated to neighborhood conditions are unlikely to directly benefit from this project.

Why it matters

Potential benefit: If successful, this could reduce health inequities and increase wellbeing and life expectancy for adults in targeted low-income neighborhoods.

How similar studies have performed: Prior single-focus neighborhood programs have shown limited and mixed results, so this bundled, concentrated-investment approach is newer and less tested but builds on promising community development ideas.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.