Computerized cognitive training for older adults with severe depression
Neuroplasticity-Based Computerized Cognitive Remediation (nCCR) for Treatment Resistant Late-Life Depression
This study is testing a new computer program that aims to help older adults with major depression who haven't found relief from regular treatments by improving their thinking skills and brain function.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-11051829 on NIH RePORTER |
What this research studies
This research investigates a new computerized cognitive training program designed to help older adults suffering from treatment-resistant major depressive disorder. The program focuses on improving cognitive control, which is often impaired in these patients, by utilizing principles of neuroplasticity to enhance brain function. Participants will engage in a randomized, double-blind trial to assess the effectiveness of this intervention compared to standard treatments. The goal is to provide a more effective treatment option for those who have not responded well to traditional antidepressant therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults diagnosed with treatment-resistant major depressive disorder.
Not a fit: Patients who do not have major depressive disorder or those who have not reached an advanced age may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could offer a novel and effective treatment option for older adults with severe depression who have not benefited from existing therapies.
How similar studies have performed: Previous research has shown promise in using cognitive remediation techniques for depression, suggesting that this approach may be effective, though this specific intervention is novel.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Morimoto, Sarah Shizuko — University of Utah
- Study coordinator: Morimoto, Sarah Shizuko
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.