Comparing two types of oral rehydration solutions for treating severe diarrhea in adults
Next generation ORS: Randomized controlled trial comparing ORS with calcium vs standard ORS in reducing severity of adults with acute watery diarrhea
This study is looking at whether a new drink with added calcium can help adults with acute watery diarrhea recover faster than the usual rehydration drink, and we're inviting people with this condition to see how well it works!
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10761797 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of a new oral rehydration solution (ORS) that includes calcium compared to the standard ORS in adults suffering from acute watery diarrhea. The study aims to understand how the addition of calcium can help restore lost ions and improve recovery from diarrhea. Participants will be randomly assigned to receive either the calcium-enhanced ORS or the standard ORS, and their recovery will be monitored to assess the severity and duration of their symptoms. This approach is based on the understanding that both monovalent and divalent ions play crucial roles in gut health during diarrheal illnesses.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing acute watery diarrhea.
Not a fit: Patients with chronic diarrhea or those who do not have acute watery diarrhea may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for adults with acute watery diarrhea, potentially reducing the severity and duration of their illness.
How similar studies have performed: Previous studies have shown promising results with similar approaches in children, but this specific investigation in adults is novel.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Cheng, Sam X — University of Florida
- Study coordinator: Cheng, Sam X
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.