Comparing two treatments for hydrocephalus in infants
Endoscopic versus Shunt Treatment of Hydrocephalus in Infants
['FUNDING_U01'] · UNIVERSITY OF UTAH · NIH-10929340
This study is looking at whether a new procedure called ETV+CPC can help babies with hydrocephalus do just as well in their thinking skills as the usual shunt treatment, but with fewer risks, and it’s for families with infants under one year old who are dealing with this condition.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-10929340 on ClinicalTrials.gov |
What this research studies
This research investigates the effectiveness of endoscopic third ventriculostomy with choroid plexus cauterization (ETV+CPC) compared to traditional cerebrospinal fluid (CSF) shunt treatment for infants with hydrocephalus. The study aims to determine if ETV+CPC can provide similar cognitive outcomes as shunt treatment while avoiding the complications associated with shunts. Families of infants under one year old who are facing hydrocephalus will be involved, and their cognitive development will be assessed using standardized tests. The goal is to provide a safer, shunt-free treatment option that maintains cognitive function.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants under 12 months of age diagnosed with hydrocephalus requiring treatment.
Not a fit: Patients with hydrocephalus who are older than one year or those who do not require surgical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could offer a safer treatment option for infants with hydrocephalus that minimizes the risk of complications associated with shunts.
How similar studies have performed: Previous research has shown that ETV+CPC is a viable treatment option, but this specific comparison of cognitive outcomes is novel.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KESTLE, JOHN — UNIVERSITY OF UTAH
- Study coordinator: KESTLE, JOHN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.