Comparing two treatment protocols for severe brain injuries in children in Latin America
Pediatric Severe Traumatic Brain Injury in Latin America – A Randomized Trial Comparing Two Management Protocols
This study is looking at two different ways to help kids with severe brain injuries and wants to find out if using special pressure monitors leads to better recovery than just relying on scans and doctor check-ups.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10913494 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of two different management protocols for children suffering from severe traumatic brain injury (sTBI). It aims to determine whether using intracranial pressure (ICP) monitoring to guide treatment leads to better outcomes compared to a protocol based solely on imaging and clinical examination. The study will be conducted in pediatric intensive care units across seven locations in Latin America, ensuring that the findings are relevant to both local and global practices. By focusing on children, the research acknowledges the unique challenges and risks associated with treating younger patients compared to adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-21 who have experienced severe traumatic brain injuries.
Not a fit: Patients who do not have severe traumatic brain injuries or are outside the age range of 0-21 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment protocols that enhance recovery and quality of life for children with severe brain injuries.
How similar studies have performed: Previous studies in adult populations have shown no significant outcome differences with ICP monitoring, highlighting the need for this novel approach in pediatric cases.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Chesnut, Randall M — University of Washington
- Study coordinator: Chesnut, Randall M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.