Comparing two surgical methods for fixing tibial plateau fractures
Official title: Arthroscopic-assisted tibial plateau fixation (AATPF) vs. Open reduction internal fixation (ORIF): A multicenter randomized controlled trial
Funded at University of Minnesota · NIH-10923964 · Data updated 2026-11-12
This study is looking at whether a newer, less invasive surgery for knee fractures works better than the traditional surgery, and it's for people who have had a tibial plateau fracture to help them recover faster and with fewer problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | September 7, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $170,861 |
| NIH project number | 5R34AR082020-02 |
| Project ID | NIH-10923964 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with lateral tibial plateau fractures who require surgical intervention.
✕Less likely to help
Patients with fractures that are not lateral tibial plateau fractures or those who are not surgical candidates may not benefit from this research.
What this research studies
This research investigates the effectiveness of arthroscopic-assisted tibial plateau fixation (AATPF) compared to the traditional open reduction internal fixation (ORIF) for treating tibial plateau fractures. The study aims to evaluate patient-reported outcomes, clinical results, and radiographic findings to determine which method leads to better recovery and fewer complications. By using a randomized controlled trial design, the research will provide high-quality evidence to guide clinical decisions and improve patient care. Patients participating in this trial will be closely monitored throughout their recovery process.
Why it matters
Potential benefit: If successful, this research could lead to improved surgical techniques that enhance recovery and reduce complications for patients with tibial plateau fractures.
How similar studies have gone: Previous studies have shown promising outcomes with arthroscopic-assisted techniques, but this research aims to provide the first Level I evidence comparing AATPF to ORIF.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Nguyen, Mai P — University of Minnesota
- Study coordinator: Nguyen, Mai P
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.