Comparing two feeding methods for very preterm infants with lung disease
Official title: Pilot trial comparing transpyloric to gastric feeding in very preterm infants with bronchopulmonary dysplasia
Funded at Stanford University · NIH-10987709 · Data updated 2026-11-12
This study is looking at whether feeding very premature babies through a different route (transpyloric feeding) instead of the usual method (gastric feeding) can help improve their health and reduce problems like reflux, especially for those with a serious lung condition called bronchopulmonary dysplasia (BPD).
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | September 5, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $386,743 |
| NIH project number | 1R21HD113897-01A1 |
| Project ID | NIH-10987709 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are very preterm infants diagnosed with bronchopulmonary dysplasia.
✕Less likely to help
Patients who are not preterm or do not have bronchopulmonary dysplasia may not benefit from this research.
What this research studies
This research investigates the effects of transpyloric feeding compared to gastric feeding in very preterm infants suffering from bronchopulmonary dysplasia (BPD). BPD is a serious lung condition that affects many premature infants, leading to long-term health issues. The study aims to determine if transpyloric feeding can improve outcomes by reducing complications associated with gastroesophageal reflux disease (GERD), which is common in these infants. By examining the safety and effectiveness of these feeding methods, the research seeks to provide better nutritional support for vulnerable infants.
Why it matters
Potential benefit: If successful, this research could lead to improved feeding strategies that enhance the health and development of very preterm infants with BPD.
How similar studies have gone: While there is limited data on transpyloric feeding in infants, similar approaches in older children and adults have shown promise, indicating potential for success in this novel application.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Jensen, Erik Allen — Stanford University
- Study coordinator: Jensen, Erik Allen
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.