Comparing two feeding methods for very preterm infants with lung disease

Pilot trial comparing transpyloric to gastric feeding in very preterm infants with bronchopulmonary dysplasia

['FUNDING_R21'] · STANFORD UNIVERSITY · NIH-10987709

This study is looking at whether feeding very premature babies through a different route (transpyloric feeding) instead of the usual method (gastric feeding) can help improve their health and reduce problems like reflux, especially for those with a serious lung condition called bronchopulmonary dysplasia (BPD).

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorSTANFORD UNIVERSITY (nih funded)
Locations1 site (STANFORD, UNITED STATES)
Trial IDNIH-10987709 on ClinicalTrials.gov

What this research studies

This research investigates the effects of transpyloric feeding compared to gastric feeding in very preterm infants suffering from bronchopulmonary dysplasia (BPD). BPD is a serious lung condition that affects many premature infants, leading to long-term health issues. The study aims to determine if transpyloric feeding can improve outcomes by reducing complications associated with gastroesophageal reflux disease (GERD), which is common in these infants. By examining the safety and effectiveness of these feeding methods, the research seeks to provide better nutritional support for vulnerable infants.

Who could benefit from this research

Good fit: Ideal candidates for this research are very preterm infants diagnosed with bronchopulmonary dysplasia.

Not a fit: Patients who are not preterm or do not have bronchopulmonary dysplasia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved feeding strategies that enhance the health and development of very preterm infants with BPD.

How similar studies have performed: While there is limited data on transpyloric feeding in infants, similar approaches in older children and adults have shown promise, indicating potential for success in this novel application.

Where this research is happening

STANFORD, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.