Comparing two approaches to help veterans with PTSD using prolonged exposure therapy.

Randomized Trial of Prolonged Exposure (PE) vs. PE with PE Coach Among Veterans with PTSD

NIH-funded research VA Puget Sound Healthcare System · NIH-10938000

This study is looking at how well a type of therapy called prolonged exposure (PE) works for veterans with PTSD, and whether using a helpful mobile app called 'PE Coach' alongside the therapy can make it even better, so veterans can feel more supported and improve their mental health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA Puget Sound Healthcare System NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-10938000 on NIH RePORTER

What this research studies

This research investigates the effectiveness of prolonged exposure (PE) therapy for veterans suffering from posttraumatic stress disorder (PTSD) and compares it to PE therapy supplemented with a mobile app called 'PE Coach'. The study aims to understand how these approaches can improve adherence to therapy and overall treatment outcomes. Veterans will engage in therapy sessions that involve recounting trauma memories and facing anxiety-provoking situations, while also using the app to help manage their treatment homework. The goal is to enhance the support provided to veterans, ultimately leading to better mental health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are veterans diagnosed with PTSD who are seeking effective treatment options.

Not a fit: Patients who do not have PTSD or those who are not veterans may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment adherence and reduced PTSD symptoms among veterans.

How similar studies have performed: Previous research has shown that prolonged exposure therapy is effective for PTSD, and the addition of supportive tools like mobile apps has shown promise in enhancing treatment adherence.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.