Comparing treatments for urinary incontinence in older women at risk of falls
Comparative effectiveness of pelvic floor muscle training, Mirabegron, and Trospium among older women with urgency urinary incontinence and high fall risk: a feasibility randomized clinical study.
This study is looking at how well three different treatments help older women who have trouble with urgent bathroom needs and are at risk of falling, by comparing pelvic floor exercises with two medications over 12 weeks to find the best way to improve their daily lives and safety.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Med Br Galveston NIH-funded |
| Lab location | 1 site (Galveston, United States) |
| Project ID | NIH-10839432 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of three different treatment options for older women experiencing urgency urinary incontinence (UUI) and at risk of falling. Participants will receive either pelvic floor muscle training led by physical therapists, a medication called Mirabegron, or another medication called Trospium Chloride over a 12-week period. The study aims to understand how these treatments impact urinary symptoms and fall risk, providing valuable insights into the best approaches for managing these conditions in older adults. By comparing these methods directly, the research seeks to identify the most effective strategies for improving quality of life and safety for older women.
Who could benefit from this research
Good fit: Ideal candidates for this research are women aged 65 and older who experience urgency urinary incontinence and are at an increased risk of falling.
Not a fit: Patients who do not experience urgency urinary incontinence or who are not at risk of falls may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment options for older women suffering from urinary incontinence, potentially reducing their risk of falls and improving their overall quality of life.
How similar studies have performed: Previous research has shown promising results with behavioral interventions and medications for urinary incontinence, but this specific comparative approach is relatively novel.
Where this research is happening
Galveston, United States
- University of Texas Med Br Galveston — Galveston, United States (Active)
Researchers
- Principal investigator: Fisher, Steven R — University of Texas Med Br Galveston
- Study coordinator: Fisher, Steven R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.