Comparing treatments for newborns experiencing opioid withdrawal

HEAL Initiative: Neonatal Opioid Withdrawal Syndrome Pharmacological Treatments Comparative Effectiveness Trial Clinical Site

NIH-funded research Univ of Arkansas for Med Scis · NIH-10924024

This study is looking at how well different medications help newborns who are going through withdrawal from opioids, and it's for babies who need extra care in hospitals or clinics that focus on women's mental health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of Arkansas for Med Scis NIH-funded
Lab location1 site (Little Rock, United States)
Project IDNIH-10924024 on NIH RePORTER

What this research studies

This research investigates the effectiveness of different pharmacological treatments for Neonatal Opioid Withdrawal Syndrome (NOWS) in newborns. Conducted at the University of Arkansas for Medical Sciences, the study aims to recruit participants from various clinics, including a specialized Women's Mental Health Program and a Neonatal Intensive Care Unit. Innovative recruitment strategies will be employed, such as attending prenatal classes and utilizing a Community Advisory Board, while follow-up care will be supported through case managers and financial incentives to ensure participant retention.

Who could benefit from this research

Good fit: Ideal candidates for this research are newborns up to 4 weeks old who are experiencing withdrawal symptoms due to maternal opioid use.

Not a fit: Patients who are not newborns or those not affected by opioid withdrawal will not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options for newborns suffering from opioid withdrawal, enhancing their health outcomes.

How similar studies have performed: Other research has shown promise in evaluating treatment options for opioid withdrawal in newborns, indicating that this approach is building on existing knowledge.

Where this research is happening

Little Rock, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.