Comparing treatments for newborns experiencing opioid withdrawal

Data Coordinating Center (DCC) for the Neonatal Opioid Withdrawal Syndrome Pharmacological Treatments Comparative Effectiveness Trial (NOWS PhaCET)

['FUNDING_OTHER'] · RESEARCH TRIANGLE INSTITUTE · NIH-10678679

This study is looking to find the best medications to help newborns who are going through withdrawal from opioids, and parents of these babies can join in to help improve treatment options for their little ones.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorRESEARCH TRIANGLE INSTITUTE (nih funded)
Locations1 site (RESEARCH TRIANGLE PARK, UNITED STATES)
Trial IDNIH-10678679 on ClinicalTrials.gov

What this research studies

This research focuses on improving the treatment of neonatal opioid withdrawal syndrome (NOWS) by conducting a large-scale, multi-center trial to compare different pharmacological treatments. The study aims to gather high-quality data to identify the most effective medications for newborns suffering from this condition. By utilizing rigorous methodologies and statistical expertise, the research will help establish best practices and clinical guidelines for treating NOWS. Parents of affected newborns may have the opportunity to participate in this important trial.

Who could benefit from this research

Good fit: Ideal candidates for participation are newborns aged 0-4 weeks who are diagnosed with neonatal opioid withdrawal syndrome.

Not a fit: Patients who are not newborns or those who do not have opioid withdrawal syndrome may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for newborns with opioid withdrawal, improving their health outcomes and quality of life.

How similar studies have performed: Previous research has shown promise in similar comparative effectiveness trials, indicating potential for success in this area.

Where this research is happening

RESEARCH TRIANGLE PARK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.