Comparing treatments for infants with opioid withdrawal syndrome
HEAL initiative: Neonatal Opioid Withdrawal Syndrome Pharmacological Treatments Comparative Effectiveness Trial: Cincinnati site
This study is looking at how well different medications help babies who are going through withdrawal after being exposed to opioids before birth, and it's for families with newborns facing this challenge at Cincinnati Children's Hospital.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-10916555 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of different medications for treating neonatal opioid withdrawal syndrome (NOWS) in infants who were exposed to opioids before birth. Conducted at Cincinnati Children's Hospital, the study aims to enroll a significant number of newborns diagnosed with NOWS and follow their progress up to the age of two. The research team, led by experienced clinicians, will assess how well these treatments work and their impact on the infants' development and health outcomes. By participating, families can contribute to vital knowledge that may improve care for future infants facing similar challenges.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants aged 0-4 weeks who have been diagnosed with neonatal opioid withdrawal syndrome.
Not a fit: Patients who are not diagnosed with neonatal opioid withdrawal syndrome or are older than 4 weeks may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment options for infants suffering from opioid withdrawal, improving their health and development.
How similar studies have performed: While there is ongoing research in this area, this specific comparative effectiveness trial is critical as optimal treatments for NOWS have not yet been established.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Merhar, Stephanie L — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Merhar, Stephanie L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.