Comparing treatments for eczema in children
Official title: Systemic Treatments and Outcomes for Pediatric Atopic Dermatitis: Setting the Stage for Comparative Effectiveness Research
Funded at Johns Hopkins University · NIH-10954351 · Data updated 2026-11-12
This study is looking at how well different medications work for kids with eczema, so we can find the best treatments that fit each child's needs.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | July 19, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $170,490 |
| NIH project number | 1R03AR084585-01 |
| Project ID | NIH-10954351 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children aged 0-18 years who have moderate-to-severe atopic dermatitis requiring systemic treatment.
✕Less likely to help
Patients with mild atopic dermatitis who do not require systemic medications may not benefit from this research.
What this research studies
This research investigates the effectiveness and safety of various systemic treatments for pediatric atopic dermatitis, commonly known as eczema, which affects many children. It aims to gather real-world data to understand how new and traditional medications perform in managing this condition. By utilizing pragmatic trials and observational studies, the research seeks to provide insights that can help tailor treatments to individual children's needs. The study will leverage large clinical research networks to enhance the understanding of treatment outcomes in diverse pediatric populations.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for children suffering from atopic dermatitis.
How similar studies have gone: Other research has shown success in using real-world data to evaluate treatment effectiveness in similar conditions, making this approach promising.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Wan, Joy — Johns Hopkins University
- Study coordinator: Wan, Joy
Related research
Other NIH-funded projects on the same topics.
-
Stopping Atopic Dermatitis and Allergy: Preventing Food Allergy by Protecting the Skin
A large study in infants at high risk for allergies tests whether using a skin barrier cream together with early, proactive skin care can prevent peanut allergy and other food allergies.
-
SEAL Study: Preventing peanut allergy by protecting baby skin
This trial tests whether using a skin-emollient and proactive skin steroids early in life can prevent peanut allergy in high-risk infants.
-
SEAL Study: Prevent allergy by protecting the baby’s skin
A very young group of high-risk babies will try a early skin-care plan to reduce eczema and prevent peanut allergy.
-
Understanding how skin fungi affect atopic dermatitis in adults
A study will look at how the skin's fungal community influences atopic dermatitis in adults and whether this understanding could lead to new treatments.
-
Preventing eczema-related allergies by strengthening infants' skin barrier
This project will see if using a trilipid skin cream plus proactive mild topical steroids in infants with early dry skin or eczema lowers their chances of developing food allergies.
-
Personalized predictions for how atopic dermatitis may progress in kids and teens
A patient-friendly plan to forecast how early-onset eczema might evolve in children and young people using simple health clues and data from diverse settings.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.