Comparing treatments for binge eating disorder
Cognitive-Behavioral and Pharmacologic Treatment of Binge Eating Disorder
This study is looking at how well a medication called lisdexamfetamine and a type of therapy called cognitive behavioral therapy can help people with binge eating disorder, and it will also check if using them together works better, while exploring other medication options for those who might not respond to the first treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10443560 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of two treatments for binge eating disorder (BED): a medication called lisdexamfetamine (LDX) and cognitive behavioral therapy (CBT). Patients will participate in a randomized controlled trial to see how well these treatments work individually and in combination. The study aims to determine not only the immediate effects of these treatments but also their long-term benefits for patients who respond positively. Additionally, it will explore alternative medication options for those who do not respond to initial treatments.
Who could benefit from this research
Good fit: Ideal candidates are individuals diagnosed with binge eating disorder, particularly those who are also obese.
Not a fit: Patients who do not have binge eating disorder or those who are not obese may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and sustained treatment options for patients with binge eating disorder.
How similar studies have performed: Previous research has shown promising results for both cognitive behavioral therapy and pharmacotherapy in treating eating disorders, but this specific combination approach is relatively novel.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Grilo, Carlos M — Yale University
- Study coordinator: Grilo, Carlos M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.