Comparing time-restricted eating and continuous calorie restriction for weight loss and colorectal cancer risk in obese adults

Effects of Time-restricted Eating versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers among Adults with Obesity

NIH-funded research University of Illinois at Chicago · NIH-10977387

This study is looking at whether eating all your meals within a set time each day can help adults with obesity lose weight and improve health markers related to colorectal cancer risk, compared to just cutting calories throughout the day.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project IDNIH-10977387 on NIH RePORTER

What this research studies

This research investigates the effects of time-restricted eating compared to daily continuous calorie restriction on body weight and markers related to colorectal cancer risk in adults with obesity. Participants will be asked to consume their daily food within a specific time window while fasting for the remaining hours. The study aims to determine if this method can lead to significant weight loss and improvements in health markers, such as blood pressure and insulin resistance. Previous pilot studies have shown that time-restricted eating is safe and may help with weight loss and reducing chronic disease risks.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults with obesity who are interested in weight loss and improving their health markers.

Not a fit: Patients who are not obese or those who have conditions that prevent them from participating in dietary interventions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective dietary approach for weight management and reducing colorectal cancer risk in obese adults.

How similar studies have performed: Previous pilot studies have shown promising results for time-restricted eating, indicating that this approach may be effective for weight loss and health improvement.

Where this research is happening

Chicago, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.