Comparing time-restricted eating and continuous calorie restriction for weight loss and colorectal cancer risk in obese adults
Official title: Effects of Time-restricted Eating versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers among Adults with Obesity
Funded at University of Illinois at Chicago · NIH-10977387 · Data updated 2026-11-12
This study is looking at whether eating all your meals within a set time each day can help adults with obesity lose weight and improve health markers related to colorectal cancer risk, compared to just cutting calories throughout the day.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project start | September 10, 2021 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $211,752 |
| NIH project number | 3R01CA257807-04S1 |
| Project ID | NIH-10977387 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults with obesity who are interested in weight loss and improving their health markers.
✕Less likely to help
Patients who are not obese or those who have conditions that prevent them from participating in dietary interventions may not benefit from this research.
What this research studies
This research investigates the effects of time-restricted eating compared to daily continuous calorie restriction on body weight and markers related to colorectal cancer risk in adults with obesity. Participants will be asked to consume their daily food within a specific time window while fasting for the remaining hours. The study aims to determine if this method can lead to significant weight loss and improvements in health markers, such as blood pressure and insulin resistance. Previous pilot studies have shown that time-restricted eating is safe and may help with weight loss and reducing chronic disease risks.
Why it matters
Potential benefit: If successful, this research could provide a new, effective dietary approach for weight management and reducing colorectal cancer risk in obese adults.
How similar studies have gone: Previous pilot studies have shown promising results for time-restricted eating, indicating that this approach may be effective for weight loss and health improvement.
Where this research is happening
-
University of Illinois at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Tussing-Humphreys, Lisa — University of Illinois at Chicago
- Study coordinator: Tussing-Humphreys, Lisa
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.