Comparing the effects of tobacco-flavored and non-tobacco flavored e-cigarettes on smoking habits
Official title: A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior
Funded at Ohio State University · NIH-11082243 · Data updated 2026-11-12
This study is looking at how different e-cigarette flavors, like tobacco and other flavors, affect how adults who smoke behave, helping to guide decisions about e-cigarette regulations.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | May 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $767,403 |
| NIH project number | 5R01DA057327-03 |
| Project ID | NIH-11082243 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adult smokers who are considering switching to e-cigarettes or are currently using them.
✕Less likely to help
Patients who do not smoke or are under the age of 21 may not receive any benefit from this research.
What this research studies
This research investigates how different flavors of e-cigarettes, specifically tobacco-flavored versus non-tobacco flavored, influence smoking behavior among adults. The study aims to provide critical data that can inform regulatory decisions by the FDA regarding e-cigarette flavors. Participants will be involved in a long-term, randomized clinical trial that examines product uptake, sustained use, and the potential for complete switching from combustible cigarettes to e-cigarettes. By understanding these dynamics, the research seeks to clarify the benefits and risks associated with e-cigarette flavors for adult smokers.
Why it matters
Potential benefit: If successful, this research could help establish guidelines for e-cigarette flavors that maximize benefits for adult smokers while minimizing risks for youth.
How similar studies have gone: While there have been studies on e-cigarette flavors, this research is unique as it aims to provide long-term, randomized clinical trial data specifically comparing tobacco and non-tobacco flavors.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Wagener, Theodore Lee — Ohio State University
- Study coordinator: Wagener, Theodore Lee
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.