Comparing the effects of tobacco-flavored and non-tobacco flavored e-cigarettes on smoking habits

A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior

NIH-funded research Ohio State University · NIH-11082243

This study is looking at how different e-cigarette flavors, like tobacco and other flavors, affect how adults who smoke behave, helping to guide decisions about e-cigarette regulations.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project IDNIH-11082243 on NIH RePORTER

What this research studies

This research investigates how different flavors of e-cigarettes, specifically tobacco-flavored versus non-tobacco flavored, influence smoking behavior among adults. The study aims to provide critical data that can inform regulatory decisions by the FDA regarding e-cigarette flavors. Participants will be involved in a long-term, randomized clinical trial that examines product uptake, sustained use, and the potential for complete switching from combustible cigarettes to e-cigarettes. By understanding these dynamics, the research seeks to clarify the benefits and risks associated with e-cigarette flavors for adult smokers.

Who could benefit from this research

Good fit: Ideal candidates for this research are adult smokers who are considering switching to e-cigarettes or are currently using them.

Not a fit: Patients who do not smoke or are under the age of 21 may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could help establish guidelines for e-cigarette flavors that maximize benefits for adult smokers while minimizing risks for youth.

How similar studies have performed: While there have been studies on e-cigarette flavors, this research is unique as it aims to provide long-term, randomized clinical trial data specifically comparing tobacco and non-tobacco flavors.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.