Comparing the effectiveness of weight loss medications for heart and metabolic health
Comparative effectiveness of anti-obesity medications for cardiometabolic health outcomes and health services use
This study looks at how various weight loss medications can help improve heart and overall health in adults with obesity, so doctors can better choose the right options for their patients trying to manage their weight and related health concerns.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Pilgrim Health Care, INC. NIH-funded |
| Lab location | 1 site (Canton, UNITED STATES) |
| Project ID | NIH-10997392 on NIH RePORTER |
What this research studies
This research investigates how different anti-obesity medications (AOMs) affect heart and metabolic health outcomes in adults with obesity. By analyzing a large dataset of insurance claims, the study aims to determine which medications are most effective and safe for long-term weight management. The findings could help guide doctors in prescribing AOMs and improve treatment options for patients struggling with obesity and related health issues. The research will also explore the impact of these medications on healthcare utilization.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are struggling with obesity and related conditions such as hypertension or diabetes.
Not a fit: Patients who are not affected by obesity or do not have related health complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide patients with more effective and safer options for managing obesity and its related health complications.
How similar studies have performed: Previous research has shown promising results with anti-obesity medications, but this study aims to provide the first comprehensive comparative effectiveness analysis, making it a novel approach.
Where this research is happening
Canton, UNITED STATES
- Harvard Pilgrim Health Care, INC. — Canton, United States (Active)
Researchers
- Principal investigator: Toh, Darren — Harvard Pilgrim Health Care, INC.
- Study coordinator: Toh, Darren
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.